Ketogenic Dietitians Research Network

KDRN Newsletter – January 2019

Project Updates

1. NICE to know

Project aim: Comparison with 2000 and 2010 surveys, to assess the impact of KD service provision across the UK and Ireland since the change in NICE guidance in 2012, and to provide a base for further research. 

Progress: Manuscript drafted, to be submitted for publication first quarter of 2019. 

2. MKDs in the UK

Project aim: To understand the core principles of MKD practice and to assess if and how the MKD differs from other KD protocols.

Progress: 

  • Manuscript submitted for publication to Journal of Human Nutrition and Dietetics. Awaiting reviewer response. 
  • Collaboration with dietitians in the United States underway to enhance understanding of international MKD practice. 

3. Nutritional Biochemistry and KDs - Projects A and B

Project A aim: Describe picture of KD biochemical testing in UK and Ireland. Compare UK practice to international guidelines.

Project B aim: Guide for dietitians regarding biochemical results in KD patients—evidence summary and suggested courses of action for abnormal results.

Progress: 

  • Project A: manuscript in progress showing significant variability amongst centres and deviance from international guidelines. Costing info included to emphasise variability. 
  • Project B: biochemical parameters that impact dietetic practice selected; literature review completed for each parameter. 

Future plans:

  • Project A: potentially devise recommendations for future practice in collaboration with medics and biochemists.
  • Project B: ongoing.

Posters & Presentations

Natasha Schoeler and Vicki Whiteley at the 6th Global Symposium in Jeju, with Dr. Kossoff and Dr. Cervenka(Johns Hopkins) 

If you are a dietitian or dietetic support worker working in ketogenic-related clinical practice, academia or industry and are interested in joining the group, or collaborating with us, we would love to hear from you! We also offer Associate Member-ship for dietitians not currently practicing in ketogenic and for other healthcare professionals. Please contact us.

1. NICE to know: impact of NICE guidelines on ketogenic diet services across the UK 

presented at British Paediatric Neurology Association (BPNA) Annual Con-ference (Jan 2018); Ketoconference (May 2018); 6th Global Symposium on Ketogenic Therapies for Neurological Disorders (Oct 2018) 

Abstract accepted at BPNA to be presented in Jan 2019 

2. Understanding the core principles of a ’modified ketogenic diet’; a UK and Ireland perspective 

presented at Ketoconference (May 2018); 6th Global Symposium on Keto-genic Therapies for Neurological Disorders (Oct 2018) 

3. Biochemical assessment of patients on a ketogenic diet: current practice in the UK and Ireland 

presented at 6th Global Symposium on Ketogenic Therapies for Neurologi-cal Disorders (Oct 2018) 

Presenters: Vicki Whiteley, Natasha Schoeler, Kirsty Martin-McGill 

Upcoming Projects

1. Lipid profiles and KDs

Project aim: 

  • To describe lipid profiles over time of patients commenced on KD. 
  • To determine clinical/dietetic actions if results deranged. 

Progress: 

  • Funding secured for student/volunteer to complete data collection. 
  • Project methods established. 

Future plans: 

  • Recruitment of student/volunteer. 
  • Retrospective data collection to include children and adults who have been or who are on a KD for drug-resistant epilepsy for at least 3 months. Initial pilot cohort of 30-50 individuals from two KD centres. 

2. Evidence-based Summary on KDs

Project aim: to produce an evidence-based summary on ketogenic diets for neurological disorders for the British Dietetic Association (BDA). Possibly in conjunction with the Diabetes specialist group. 

Progress: in liaison with BDA. 

Future plans: clarification of aims and summary template. Likely to start in summer—May onwards. 

Volunteers Welcome!

Please contact us if you would like to get involved with any of our projects. Collaborations are invaluable for gaining research experience and building relationships with other KD centres.

Resources

NEW resources available!

‘Non-prescribable “keto” products’ and ‘Ketogenic shopping list’

Many thanks to Alison Craig (Daisy Garland Dietitian, Leeds Children’s Hospital) and Lucy Blackstone (Paediatric Dietitian, Manchester Children’s Hospital) for working on these.  Please contact zoe.simpson@gosh.nhs.uk if you would like a copy. 

News

KDRN Website

KDRN now has its own WEBSITE! Many thanks to our Co-Publicist, Hannah Taylor, for leading on this. This will be a platform for sharing information on projects and meetings. Please request access here. 

KetoConference 2019

KetoConference 2019 will be held on Tuesday 14th May at The Engineers House, The Promenade, Clifton Down, Avon, Bristol BS8 3NB. The next KDRN meeting (our AGM) will be linked with this event, held on Wed 15th May. Further details to follow! 

Library Notes

Our KDRN librarian, Bridget Lambert (Clinical Science Dietitian, Vitaflo International Ltd), has created a summary of selected recent publications, including: 

Optimal clinical management of children receiving dietary therapies for epilepsy 

Use of the KD in conditions other than epilepsy 

The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet 

Effect of modified Atkins diet in adults with drug-resistant focal epilepsy: A ran-domized clinical trial 

Please contact zoe.simpson@gosh.nhs.uk if you would like a copy of the full library notes. 

Project ideas WELCOME!

If you are a dietitian or dietetic support worker working in ketogenic-related clinical practice, academia or industry and are interested in joining the group, or collaborating with us, we would love to hear from you! We also offer Associate Membership for dietitians not currently practicing in ketogenic and for other healthcare professionals. 

Please contact us.